Severe injection site reaction to insulin detemir.

to slowly improve the FBG concentrations over a period of continuous use. Surprisingly, this effect was rapidly reversed when the treatment ceased, as blood glucose retuned to pretreatment levels within 15–20 days. Those subjects who started to take the herbal remedy again after the withdrawal period showed a more rapid decline in their FBG concentrations than when they first started the treatment. It is unclear from this study whether the FBG would return to euglycemia over a longer period of time, but it appears that the rate of decline slows and may plateau before this was reached. This study strongly suggests that this combination of traditional Chinese herbs, together with chromium, may be effective in improving glycemic control in people diagnosed with type 2 diabetes. The mechanism of action remains unclear and may be a combination of an increase in insulin responsiveness and glucose uptake. The relative importance of the individual component herbs is also unknown, and we are undertaking further studies to investigate this.